Runeword
Venom
TalDolMal
- Sockets
- 3
- Required level
- 49
- Item types
- Weapons
- Ladder
- All modes
Properties
- Hit Causes Monster To Flee +25%
- Prevent Monster Heal
- Ignore Target's Defense
- 7% Mana Stolen Per Hit
- Level 15 Poison Explosion (27 Charges)
- Level 13 Poison Nova (11 Charges)
- +273 Poison Damage Over 6 seconds
Who uses Venom
Venom is a weapon runeword that requires three sockets and a level of 49. Its gimmick is to combine poison damage with effects that make monsters flee, prevent healing, and ignore defense, allowing the poison to wear down enemies over time. However, it lacks enhanced damage and attack speed, so it is not effective for most physical attack builds. Notably, it is the only runeword that can be placed in a Sorceress Orb, though its utility there is limited. The runes are moderately common, but the lack of offensive punch keeps it from being a popular choice. It is not ladder-only.
FAQ
- What runes make Venom?
- Tal, Dol, Mal in that order, in a 3-socket item.
- What items can Venom be made in?
- Weapons.
- Is Venom ladder only?
- No, it can be made in any game mode.
Introduced in patch 1.09. Names and numbers compiled from the Diablo Wiki (CC BY-SA 3.0); sources: fandom-runewords. Last verified patch 3.3, 2026-09-12.